SynthesisFrontiers in pediatrics2025
Diagnostic accuracy of lung ultrasound score for bronchopulmonary dysplasia in preterm neonates: a systematic review and meta-analysis.
Synthesis in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Lung Ultrasound in Bronchopulmonary Dysplasia: Diagnostic Tool, Prognostic Marker or Monitoring Strategy?Children (Basel, Switzerland) · 2026Review
- The Diagnostic Value of Lung Ultrasound in Bronchopulmonary Dysplasia Among Preterm Infants with Gestational Age ≤ 28 Weeks.Diagnostics (Basel, Switzerland) · 2026Article
- Lung ultrasound for neonatal respiratory distress in a resource-limited county hospital: a pilot study.BMC pediatrics · 2026Observational
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bronchopulmonary dysplasia (BPD) remains common among preterm infants, yet diagnostic criteria rely on post-hoc oxygen requirements and radiography. Semiquantitative lung ultrasound (LUS) scoring offers a radiation-free, bedside alternative. We sought to determine the time-dependent diagnostic accuracy of LUS scores for BPD in preterm neonates. Methods: We performed a systematic review and meta-analysis of studies reporting LUS scores in preterm neonates (born at <37 gestational weeks) with BPD. We searched five databases through June 2025. We stratified data into four postnatal age timepoints (days 1-3, 7, 14, and 21) and pooled them using bivariate random-effects models to estimate sensitivity, specificity, likelihood ratios, diagnostic odds ratios, and area under the hierarchical summary receiver-operating characteristic (HSROC) curve. Results: We included data from 22 studies ( Conclusion: The diagnostic accuracy of LUS scoring for BPD improved from the first through the third weeks of life, approaching optimal levels by day 21. These findings support the integration of serial LUS assessments into neonatal care plans to enable earlier, non-invasive BPD diagnosis. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251085780, PROSPERO CRD420251085780.
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