ArticleADMET & DMPK2025
Y-Co metal-organic framework for sensitive electrochemical determination of doxorubicin hydrochloride.
Article in ADMET & DMPK, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- A molecularly imprinted electrochemical sensor for detection of bisphenol A based on dendritic Pt-Pd bimetallic nanoparticles and g-CMikrochimica acta · 2026Article
- Waste-derived nanocomposite carbon paste electrochemical sensor for the first guadipyr monitoring in agri-environmental samples: a sustainable platform for on-site analysis.BMC chemistry · 2026Article
- Highly sensitive voltammetric determination of Pb²⁺ and Cd²⁺ ions using a carbon paste electrode modified with Mn₀.₅Zn₀.₅Fe₂O₄ spinel ferrite nanoparticles.Scientific reports · 2026Article
- Surfactant/β-cyclodextrin inclusion-mediated nucleic acid enrichment for ratiometric electrochemical sensing of low-abundance Staphylococcus aureus.Mikrochimica acta · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and purpose: Cancer represents a major challenge to public health; therefore, identifying doxorubicin hydrochloride (DOX·HCl) as an important chemotherapy drug holds considerable significance. Experimental approach: An electrochemical sensing strategy was designed for DOX·HCl determination by using Y-Co bimetallic metal-organic framework (Y-Co MOF) modified carbon paste electrode (CPE). The Y-Co-MOF was successfully prepared via the solvothermal method. Key results: Characterizations using field emission scanning electron microscopy, transmission electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy and energy-dispersive X-ray spectroscopy with elemental mapping images were used to evaluate the morphological features, crystalline structure, functional groups, and elemental composition of the Y-Co-MOF. From cyclic voltammetric studies, well-defined redox peaks of DOX·HCl with improved response peak currents at lower overpotentials were observed on the surface of Y-Co MOF/CPE compared to the unmodified CPE. This indicated that the as-prepared modified CPE has a strong and efficient redox capability toward DOX·HCl. Under the optimized parameters and conditions, the linear response range from differential pulse voltammetry measurements for DOX·HCl were 0.0025 to 100.0 μM, with a low limit of detection of 0.001 μM. Finally, the ability of the designed sensing platform to determine the amounts of DOX·HCl in the injection sample was studied and it has been observed a high and efficient ability with satisfactory values of recovery and relative standard deviation. Conclusion: This analytical approach offers a useful means for the analysis of pharmaceutical formulations, providing potential advantages in cancer therapy.
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