ArticleIntegrative organismal biology (Oxford, England)2025
Early Developmental Decline in HSP Expression Affects Subsequent Response to Transient Heat Exposure.
Article in Integrative organismal biology (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Understanding physiological responses to short-term changes in temperature is of growing interest considering the rising frequency and severity of transient temperatures such as heat waves. During the embryonic development of egg-laying vertebrates, inducible physiological responses to transient heat are likely critical to short-term survival but may also be energetically costly or disruptive to development. Inducible heat-shock proteins (HSPs) are conserved molecular chaperones which act to safeguard cellular protein homeostasis during transient stress. However, experiments in ectotherms have shown that overexpression of HSPs can increase embryonic mortality and reduce later thermotolerance. Yet, few studies have explored natural developmental patterns of
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