ArticleQatar medical journal2025
Assessing the determinants and association of cognitive memory performance with blood folate and cobalamin levels in Qatar's healthy aging population.
Article in Qatar medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Cognitive health, crucial for the independence and quality of life in older adults, is influenced by various factors, including nutritional status, which is increasingly recognized for its importance. Folate (vitamin B9) and cobalamin (vitamin B12) are essential for neurological health. Despite most studies offering broad global insights, this research addresses the knowledge gap regarding the relationship between folate and cobalamin levels and cognitive memory performance in a cognitively healthy aging adult. The primary objective of this study is to examine the relationship between memory performance and blood levels of folate and cobalamin, as well as to identify the determinants of memory performance, in adults in Qatar. Methods: We conducted a cross-sectional analysis of the data obtained from Qatar Biobank. This study assessed cognitive performance using the Cambridge Neuropsychological Test Automated Battery and measured blood concentrations of folate and cobalamin. Additionally, we examined demographic, lifestyle, behavioral, and disease-related factors as determinants of memory performance. We used multivariable linear regression to identify associations between Paired Associated Learning First Attempt Memory (PALFAMS) and vitamin levels. Results: Six hundred and thirty-six individuals aged 40 years and older were included in this study. The z-scores for blood levels of folate and cobalamin were each found to be positively associated with the PALFAMS (β, 0.17 [95% CI, -0.188 to 0.538]; Conclusion: Since the associations between blood levels of folate and cobalamin and memory performance were not statistically significant, these results underscore the need for more comprehensive studies to explore the complex relationships between nutrition and memory performance, ultimately guiding more effective strategies for the prevention and management of memory impairment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.