Evidence map›Paper›PMID 41480223›Full record

ArticleWorld journal of gastrointestinal oncology2025

Early and late-onset colorectal cancer in African Americans during COVID-19.

Lakshmi G Chirumamilla, Hassan Brim, Suryanarayana R Challa, Gholamreza Oskrochi, Mrinalini Deverapalli, Rumaisa Rashid, Mudasir Rashid, Farshad Aduli, Angesom Kibreab, Adeyinka Laiyemo and 6 more

Abstract read
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Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Lakshmi G ChirumamillaDepartment of Medicine, Gastroenterology Division and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Hassan BrimDepartment of Pathology and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Suryanarayana R ChallaDepartment of Medicine, Gastroenterology Division and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Gholamreza OskrochiCollege of Engineering and Technology, American University of the Middle East, Egaila 54200, Kuwait.
Mrinalini DeverapalliDepartment of Medicine and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Rumaisa RashidDepartment of Medicine and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Mudasir RashidDepartment of Medicine and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Farshad AduliDepartment of Medicine, Gastroenterology Division and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Angesom KibreabDepartment of Medicine, Gastroenterology Division and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Adeyinka LaiyemoDepartment of Medicine, Gastroenterology Division and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Zaki A SherifDepartment of Biochemistry and Molecular Biology, Howard University College of Medicine, Washington, DC 20060, United States.
Nader ShayeghDepartment of Medicine and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Babak ShokraniDepartment of Medicine, Gastroenterology Division and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
Rabia ZafarDepartment of Pathology and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States.
John M CarethersDepartment of Medicine, Moores Cancer Center, and Wertheim School of Public Health and Human Longevity, University of California San Diego, California, CA 92093, United States.
Hassan AshktorabDepartment of Medicine and Cancer Center, Howard University College of Medicine, Washington, DC 20060, United States. hashktorab@howard.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of early-onset colorectal cancer (EOCRC, < 45 years of age at onset) is on the rise among adults, including African Americans (AA).

aimTo examine differences between EOCRC and late-onset colorectal cancer (LOCRC) among AA patients and any effect during coronavirus disease (COVID) by comparing data during pre-COVID (2015-2019) and the COVID era (2020-2023).

methodsWe conducted a retrospective review of Howard University Hospital records from 2015 to 2023 for colorectal cancer patients that included demographics, clinicals, pathology, and colonoscopy records. A three-year interval analysis was performed to compare post-COVID era (2020-2023) to preceding years to discern temporal trends.

resultsThe study included 138 LOCRC and 13 EOCRC cases of which > 80% of patients were AA. Compared to pre-COVID, LOCRC cases increased in number from 55 to 83, and EOCRC cases increased from 6 to 7 during COVID. There was no change in mean age for LOCRC (64.7 years

conclusionWe report increase in colorectal cancer cases during the COVID-19 era, especially among young AA males. EOCRC and LOCRC patients showed distal location predominance, most commonly in recto-sigmoid region. The decrease in staging or metastasis, which might be due to growing awareness and earlier detection among patients.

Indexed as

African AmericansColorectal cancerCOVID-19Early-onsetLate-onset

Identifiers

PMID41480223
PMCPMC12754293

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