Evidence map›Paper›PMID 41480205›Full record

ArticleWorld journal of gastrointestinal oncology2025

Pancreatic neuroendocrine microtumors in the elderly: A retrospective study using cadaveric pancreatic tissue.

Ting Yang, Ke Ren, Xiang-Quan Chen, Taku Toriumi, Yutaro Natsuyama, Jun Li, Aoi Sukeda, Toshitaka Nagao, Shuang-Qin Yi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ting YangDepartment of Frontier Health Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo 116-8551, Japan.
Ke RenFaculty of Physical Education, Qujing Normal University, Qujing 655000, Yunnan Province, China.
Xiang-Quan ChenFaculty of Physical Education, Qujing Normal University, Qujing 655000, Yunnan Province, China.
Taku ToriumiDepartment of 1 Anatomy, Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8037, Japan.
Yutaro NatsuyamaDepartment of Anatomy, Tokyo Medical University, Tokyo 160-0022, Japan.
Jun LiState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.
Aoi SukedaDepartment of Anatomic Pathology, Tokyo Medical University Hospital, Tokyo 160-0023, Japan.
Toshitaka NagaoDepartment of Anatomic Pathology, Tokyo Medical University Hospital, Tokyo 160-0023, Japan.
Shuang-Qin YiDepartment of Frontier Health Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo 116-8551, Japan. yittmniu@tmu.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic neuroendocrine microtumors (PNEMTs) are small (< 5 mm), non-functioning, well-differentiated neuroendocrine neoplasms. Although they are rare, they are not invariably benign. PNEMTs are typically discovered incidentally during autopsy. However, data regarding the occurrence of PNEMTs in the elderly population, particularly those identified incidentally in cadaveric studies, remain limited.

aimTo investigate the prevalence and histopathological characteristics of PNEMTs in elderly individuals by analyzing cadaveric pancreatic tissues.

methodsWe conducted a retrospective analysis of 85 pancreatic specimens (age range: 58-109 years) obtained from cadavers for anatomical education and research at the Department of Life Dentistry, Nippon Dental University. Paraffin sections of the pancreatic head, body, and tail were prepared for histological and immunohistochemical analysis.

resultsFive cases with PNEMTs (5/85, 5.9%; male,

conclusionSmall, predominantly low-grade, GLU-secreting PNEMTs were present in 5.9% of elderly individuals, highlighting the prevalence of subclinical PNEMTs and the need for careful follow-up.

Indexed as

Cadaveric studyChromogranin AElderly populationsNon-functioning tumorPancreatic neuroendocrine microtumorsSynaptophysinWell-differentiated pancreatic neuroendocrine neoplasms

Identifiers

PMID41480205
PMCPMC12754284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.