Evidence map›Paper›PMID 41480191›Full record

ArticleInternational journal of biomaterials2025

Bacterial Extracellular Vesicles (BEVs) Derived From

Sushmita Das, Subrata Das, Subhadeep Gupta, Afruja Khan, Pradip Kumar Tarafdar, Amirul Islam Mallick

Abstract read
In one paragraph

Article in International journal of biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Bacterial Extracellular Vesicles (BEVs) Derived FromInternational journal of biomaterials · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sushmita DasDepartment of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, Nadia, West Bengal, 741246, India, iiserkol.ac.in.ORCID https://orcid.org/0009-0005-2175-5378
Subrata DasDepartment of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, Nadia, West Bengal, 741246, India, iiserkol.ac.in.ORCID https://orcid.org/0009-0001-4170-080X
Subhadeep GuptaDepartment of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, Nadia, West Bengal, 741246, India, iiserkol.ac.in.ORCID https://orcid.org/0000-0002-2407-2741
Afruja KhanDepartment of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, Nadia, West Bengal, 741246, India, iiserkol.ac.in.ORCID https://orcid.org/0000-0003-4492-5323
Pradip Kumar TarafdarDepartment of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, Nadia, West Bengal, 741246, India, iiserkol.ac.in.ORCID https://orcid.org/0000-0002-1059-950X
Amirul Islam MallickDepartment of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, Nadia, West Bengal, 741246, India, iiserkol.ac.in.ORCID https://orcid.org/0000-0002-2265-9856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in drug delivery technologies involve the extracellular vesicles as a promising bioactive drug delivery vehicle expected to improve targeted therapeutic delivery in pharmaceutical innovations. Recently, Gram-negative bacterial extracellular vesicles (outer membrane vesicles or OMVs) have gained attention for their role in host-microbe interactions and potential in drug delivery. Bacterial extracellular vesicle (BEV) shedding is a conserved mechanism of intra- and interspecies communication, providing critical insights into host-microbe interactions. However, the biogenesis and compositional diversity of BEVs produced by Gram-positive bacteria remain underexplored. Understanding the translational application potential of BEVs remains elusive due to the suboptimal isolation of BEVs and limited structural-functional characterization. A comprehensive study to develop BEVs as delivery vehicles will provide critical insights into the perspective of microbial-host interplay and illuminate the modulation of the drug delivery strategy. Here, using a food-grade probiotic

Indexed as

Antimicrobial and anticancer drug deliverybacterial extracellular vesicles (BEVs)Lactococcus lactis

Identifiers

PMID41480191
PMCPMC12755118

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.