Effects of Exposure to High Temperature and Combustion by Products on Firefighter Saliva: An Evaluation of PH, Flow, TNF-α, IL-6, IL-10, Lactoferrin and Lysozyme.

R Trujillo Junior, D A Passareti, A Coelho Boggi, H Horiuti Soares, A L Lacerda Bachi, R R Fujita, G S Amaral, J B do Amaral, R Pezato

Abstract read

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In one paragraph

Article in Annals of burns and fire disasters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

R Trujillo JuniorFire Department, Escola Superior de Bombeiros, Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.

D A PassaretiFire Department, Escola Superior de Bombeiros, Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.

A Coelho BoggiFire Department, Escola Superior de Bombeiros, Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.

H Horiuti SoaresFire Department, Escola Superior de Bombeiros, Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.

A L Lacerda BachiPost-Graduation Program in Health Sciences, Santo Amaro University (UNISA), São Paulo, Brazil.

R R FujitaDepartment of Otorhinolaryngology, Head and Neck Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.

G S AmaralFire Department, Escola Superior de Bombeiros, Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.

J B do AmaralENT Research Lab, Department of Otorhinolaryngology, Head and Neck Surgery, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.

R PezatoFire Department, Escola Superior de Bombeiros, Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a longitudinal study of 40 firefighters, in which the effects of firefighting on saliva were investigated using firefighting simulators. Salivary concentrations of TNF-α, IL-6, IL-10, lactoferrin and lysozyme were measured using the ELISA method, and salivary volume and pH were measured before and after firefighting exposure. The concentrations of TNF-α, IL-6, lactoferrin and lysozyme showed no significant changes, in contrast there was a decrease in the concentrations of IL-10 in pH and saliva production of firefighters after acute exposure to firefighting. We conclude that firefighting alters the composition of saliva.

Indexed as

antimicrobial peptidesheatimmune barrierinterleukinssalivary composition

Identifiers

PMID41480138

PMCPMC12755367

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.