Evidence map›Paper›PMID 41480108›Full record

ArticleFrontiers in microbiology2025

Emergence of KPC-2 and NDM-13-coproducing carbapenem-resistant hypervirulent

Jia Tao, Liru Wang, Na Yang, Hui Fu, Xinxin Hu, Tingyu Lai, Jianning Jin, Gang Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jia TaoCenter of Medical Laboratory, General Hospital of Ningxia Medical University, Yinchuan, China.
Liru Wang *Center of Medical Laboratory, General Hospital of Ningxia Medical University, Yinchuan, China.
Na YangNingxia Key Laboratory of Clinical and Pathogenic Microbiology, General Hospital of Ningxia Medical University, Yinchuan, China.
Hui Fu *Center of Medical Laboratory, General Hospital of Ningxia Medical University, Yinchuan, China.
Xinxin HuTraditional Chinese Medicine Department, General Hospital of Ningxia Medical University, Yinchuan, China.
Tingyu LaiSchool of Laboratory Medicine, Ningxia Medical University, Yinchuan, China.
Jianning Jin *Traditional Chinese Medicine Department, General Hospital of Ningxia Medical University, Yinchuan, China.
Gang LiCenter of Medical Laboratory, General Hospital of Ningxia Medical University, Yinchuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carbapenem-resistant hypervirulent Methods: The Results: The CR-hvKp strain A51198714 exhibited resistance to nearly all tested antibiotics, including ceftazidime-avibactam and aztreonam. PCR and Sanger sequencing confirmed the co-occurrence of Conclusion: This study reports a clinical ST11-K64 CR-hvKP strain co-producing KPC-2 and NDM-13, which carried multiple resistance genes on two resistant plasmids, along with virulence factors enhancing its pathogenicity. These findings underscore the imperative for enhanced surveillance to mitigate the dissemination of such high-risk, multidrug-resistant, and hypervirulent strains.

Indexed as

co-producinghypervirulenceKlebsiella pneumoniaeKPC-2NDM-13

Identifiers

PMID41480108
PMCPMC12753936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.