Evidence map›Paper›PMID 41479941›Full record

ArticleWorld journal of gastrointestinal endoscopy2025

Advances in endoscopic dysplasia detection in inflammatory bowel disease.

Partha Pal, Priyaranjan Kata, Zaheer Nabi, Mohan Ramchandani, Pramod Reddy Soma, Rajesh Gupta, Manu Tandan, Nageshwar Reddy Duvvur

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Article in World journal of gastrointestinal endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Partha PalDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India. partha0123456789@gmail.com.
Priyaranjan KataDepartment of Medicine, MedStar St. Mary's Hospital, Leonardtown, MD 20650, United States.
Zaheer NabiDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.
Mohan RamchandaniDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.
Pramod Reddy SomaDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.
Rajesh GuptaDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.
Manu TandanDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.
Nageshwar Reddy DuvvurDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDysplasia surveillance in inflammatory bowel disease (IBD) has evolved significantly with the adoption of advanced endoscopic technologies.

aimTo synthesize evidence on image-enhanced endoscopy techniques, biopsy protocols, and surveillance practices optimizing dysplasia detection in IBD.

methodsA scoping review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A comprehensive search of PubMed and EMBASE from inception to June 2025 identified studies reporting on endoscopic dysplasia detection or characterization in IBD. Forty-five studies were included for qualitative synthesis, covering dye-based chromoendoscopy (DCE), virtual chromoendoscopy (VCE), confocal laser endomicroscopy, artificial intelligence-based tools, and panoramic endoscopy.

resultsDCE consistently demonstrated high dysplasia detection rates, especially when indigo carmine was used, and enabled accurate pit-pattern-based lesion characterization. High definition (HD) DCE may offer procedural benefits over HD white light endoscopy (WLE), though superiority in dysplasia detection remains inconsistent across studies. In comparative studies, DCE outperformed or matched white-light approaches, with higher dysplasia yield in selected trials (

conclusionImage-enhanced targeted surveillance - particularly using DCE or validated virtual platforms - has improved dysplasia detection in IBD and may allow for a reduction in random biopsies. Despite technological advancements, major quality gaps and interobserver variability persist in clinical practice. Standardized training, quality benchmarks, and cost-effective implementation of advanced endoscopic techniques are needed to optimize colorectal cancer prevention in IBD.

Indexed as

BiopsyColitis-associated neoplasiaDye-based chromoendoscopyDysplasiaHigh-definition endoscopyNarrow band imagingVirtual chromoendoscopyWhite light endoscopy

Identifiers

PMID41479941
PMCPMC12754194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.