ArticleFrontiers in human neuroscience2025
Altering visual feedback during reaching: no mitigating effect on pain for individuals with complex regional pain syndrome, but visuomotor adaptation is preserved.
Article in Frontiers in human neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Complex regional pain syndrome (CRPS) is often associated with pain-related fear of movement, and virtual reality has been proposed as a potential rehabilitation intervention to overcome this issue. Therefore, this cross-sectional study aimed to test whether altering the visual feedback (VF) on movement could mitigate pain and promote movement. Methods: Fifteen participants with upper-limb CRPS and 15 age- and gender-matched pain-free participants undertook a target reaching task in the Kinarm exoskeleton, with two VF conditions being tested (Per Exposure: GREATER or SMALLER VF; two separate sessions), preceded and followed by reaching movements without VF (Pre-/Post-Exposure). Proprioception was assessed with a Limb Position Sense task, and a Movement Accuracy outcome was derived from the Pre-Exposure reaching movements. Results: Contrary to our hypothesis, pain intensity was not influenced by VF conditions but increased over Time ( Discussion: These findings support the idea that visuomotor adaptation is preserved in CRPS and can be used to promote movement.
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