Evidence map›Paper›PMID 41479829›Full record

ReviewWorld journal of nephrology2025

Role of antiphospholipid antibodies in kidney disease: Risk factors, immunopathogenesis, and diagnosis.

Khawar Abbas, Rubina Naqvi, Wajiha Musharraf, Muhammed Mubarak, Jawahar Lal

Abstract readReview
In one paragraph

Review in World journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Renal Vein Thrombosis: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khawar AbbasDepartment of Immunology, Sindh Institute of Urology and Transplantation, Karachi 74200, Sindh, Pakistan. drkhawar_imuno@yahoo.com.
Rubina NaqviDepartment of Nephrology, Sindh Institute of Urology & Transplantation, Karachi 74200, Sindh, Pakistan.
Wajiha MusharrafDepartment of Immunology, Sindh Institute of Urology and Transplantation, Karachi 74200, Sindh, Pakistan.
Muhammed MubarakDepartment of Histopathology, Sindh Institute of Urology and Transplantation, Karachi 74200, Sindh, Pakistan.
Jawahar LalDepartment of Internal Medicine, Sindh Institute of Urology and Transplantation, Karachi 74200, Sindh, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiphospholipid antibodies (aPLs) are a heterogeneous group of autoantibodies that include anticardiolipin antibodies, anti-β2 glycoprotein I antibodies, and lupus anticoagulant. The presence of aPLs is the main characteristic feature of antiphospholipid syndrome (APS), an autoimmune disease with multifactorial etiology. Kidney involvement is a well-recognized complication associated with both primary and secondary APS. Kidney involvement in APS presents with renal artery thrombosis, renal vein thrombosis, allograft loss due to thrombosis after kidney transplantation, and injury to the renal microvasculature, also known as APS nephropathy (APSN). APSN is the characteristic manifestation of kidney involvement in APS and occurs as a result of vaso-occlusive disease in the intrarenal vasculature. Diagnosis and risk stratification of APS are complex and still evolving. This review synthesizes and updates the available evidence in literature regarding risk factors, pathogenesis, and diagnosis of APS and APSN.

Indexed as

AllograftAntiphospholipid antibodiesAntiphospholipid nephropathyAntiphospholipid syndromeKidney infarctionThrombosis

Identifiers

PMID41479829
PMCPMC12754509

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.