ReviewFrontiers in oncology2025
Current status and upcoming developments for online adaptive proton therapy enabling a closed feedback loop for near real-time adaptation.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Online adaptive radiotherapy: International strategies for AI-enabled workflow efficiency and radiation therapist-led delivery for sustainable practice.Technical innovations & patient support in radiation oncology · 2026Article
- Towards automated dose-guided patient positioning at clinical timescale in head-and-neck cancer proton radiotherapy.Medical physics · 2026Article
- Beyond Couch Correction in Head and Neck Radiotherapy: A Narrative Review of Action-Oriented Positioning Management.Cancers · 2026Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proton therapy (PT) has the potential to deliver conformal doses to the tumor while sparing normal tissue, but is highly susceptible to treatment uncertainties. The occurrence of anatomical changes during PT treatments has a major impact on the delivered dose, often necessitating plan adaptations that are typically performed offline and require a few days before the adapted plan is ready. In order to react promptly to detected anatomical changes, online adaptive proton therapy (OAPT) has been proposed with the goal of adapting the plan while the patient is on the treatment couch. First OAPT workflows for daily plan adaptation that are effective against interfractional anatomical variations have reached clinical application. However, even faster OAPT workflows are needed to cope with faster anatomical changes. Near real-time adaptive PT (NAPT) relying on online
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.