Evidence map›Paper›PMID 41479784›Full record

ArticleFrontiers in oncology2025

The role of a multidisciplinary clinic for management of patients with IDH mutant gliomas.

Lauren Aucoin, Jessica W Templer, Matthew C Tate, Karan S Dixit

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lauren AucoinDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States.
Jessica W TemplerDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States.
Matthew C TateDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States.
Karan S DixitDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Management of IDH-mutant lower-grade gliomas (IDHm LGGs) is complex, requiring careful balance between tumor control as well as neurocognitive function and quality of life. While multidisciplinary clinics improve outcomes in other cancers, no structured model exists for IDHm LGGs. Methods: We present a framework for a multidisciplinary clinic a dedicated to patients with IDHm LGGs. Discussion: IDHm LGGs, including WHO grade 2 astrocytomas and oligodendrogliomas, affect younger adults with median survivals exceeding a decade. Tumor related seizures are a significant source of distress for patients with IDHm LGGs, in addition to burden of disease. Treatment decisions such as surgery, medical therapy, and radiation, along with seizure management are highly individualized and benefit from coordinated, longitudinal care. A dedicated multidisciplinary LGG clinic integrates expertise across neurosurgery, neuro-oncology, epilepsy, and neuropsychology to optimize outcomes and patient experience to create a onco-functional balance. Conclusion: A multidisciplinary clinic dedicated to IDHm LGGs can provide a collaborative model for comprehensive, patient-centered care for a rare and complex disease which may be replicated at other brain tumor centers.

Indexed as

IDH mutant gliomalow grade gliomamultidisciplinary carequality of lifetumoral epilepsy

Identifiers

PMID41479784
PMCPMC12753466

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.