SynthesisFrontiers in oncology2025
Global research trends in signaling pathways of spasmolytic polypeptide-expressing metaplasia pathogenesis: a bibliometric analysis.
Synthesis in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Signaling pathways associated with spasmolytic polypeptide-expressing metaplasia (SPEM) pathogenesis play a critical role in disease development, particularly in gastric cancer precursor lesions. However, global research trends in signaling pathways in SPEM pathogenesis remain undetermined. This study aims to fill this gap by conducting a comprehensive bibliometric analysis to map the field, identify key insights, and guide future research directions. Methods: Articles and reviews were retrieved from the Web of Science Core Collection up to June 8 2025. Bibliometric analysis and knowledge mapping were conducted via CiteSpace and VOSviewer. Results: A total of 89 papers from 221 institutions, 719 authors, and 56 journals across 21 countries/regions were included. The number of publications is growing slowly. Conclusion: By systematically reviewing signaling pathways in SPEM pathogenesis, this study provides critical guidance for future research strategic planning and collaboration. It highlights the urgent need for strengthened interdisciplinary and global partnerships to drive progress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.