ArticleWorld journal of clinical cases2025
Risk of incident pancreatitis in patients with celiac disease: A population-based matched retrospective cohort study.
Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Long-term risk of acute pancreatitis in patients with celiac disease: A nationwide population-based cohort study.Journal of internal medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCeliac disease (CD) is an autoimmune disorder associated with an increased risk of pancreatitis, yet large-scale studies examining long-term risk and specific etiologies in CD patients are scarce.
aimTo assess the long-term risk of pancreatitis in CD patients.
methodsWe conducted a population-based cohort study with consecutive patients diagnosed with CD using the TriNeTx research network. Each patient was matched to a patient in the control group using a 1:1 propensity score matching to minimize confounding effects. The primary outcomes were the incidence of acute pancreatitis and chronic pancreatitis, and the secondary outcome was to assess the etiologies of pancreatitis. The incidence was estimated using a Cox proportional hazards model with a hazard ratio (HR) and 95% confidence interval (CI).
resultsA total of 160228 patients were identified to have CD, and the remaining 250725 individuals without CD were considered as controls. At 7-year follow-up, CD patients exhibited a significantly higher risk of acute pancreatitis (HR = 2.05; 95%CI: 1.93-2.17) and chronic pancreatitis (HR = 1.42; 95%CI: 1.31-1.54) compared to controls. Elevated risks for alcohol-induced (HR = 1.35), biliary (HR = 1.37), and idiopathic pancreatitis (HR = 1.49) were also observed. Findings remained robust across all follow-up intervals and sensitivity analyses.
conclusionPatients with CD have a substantially increased long-term risk of acute and chronic pancreatitis, including alcohol-related, biliary, and idiopathic subtypes. These findings support the routine surveillance of pancreatitis in CD management and highlight the need for further research into disease-specific risk factors and mitigation approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.