Evidence map›Paper›PMID 41479638›Full record

ReviewWorld journal of gastroenterology2025

Advances in endoscopic ultrasound-guided shear wave elastography: A comprehensive review of its clinical applications.

Mattia Paratore, Sara Miliani, Giulia D'Acunzo, Nicholas Viceconti, Silvia Andaloro, Giuseppe Cerniglia, Fabrizio Mancuso, Elena Melita, Gianenrico Rizzatti, Antonio Gasbarrini and 2 more

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mattia ParatoreDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Sara MilianiDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Giulia D'AcunzoDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Nicholas VicecontiDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Silvia AndaloroDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Giuseppe CernigliaDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Fabrizio MancusoDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Elena MelitaDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Gianenrico RizzattiDigestive Endoscopy Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Antonio GasbarriniInternal Medicine and Gastroenterology Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Laura RiccardiDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Matteo GarcovichDiagnostic and Interventional Ultrasound Unit, CEMAD Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy. matteo.garcovich@policlinicogemelli.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic ultrasound-guided shear wave elastography (EUS-SWE) represents a significant advancement in non-invasive tissue characterization, enabling objective assessment of quantitative tissue stiffness in real-time with potential clinical relevance across a variety of gastrointestinal disorders. Recent developments in EUS-SWE have expanded its application beyond hepatic fibrosis to include pancreatic diseases and the evaluation of solid tumors. EUS-SWE has demonstrated diagnostic accuracy comparable to vibration-controlled transient elastography in assessing fibrosis stages, positioning it as a potential alternative to liver biopsy. Moreover, EUS-SWE has shown promise in evaluating pancreatic tissue stiffness, aiding in the diagnosis and monitoring of chronic pancreatitis and pancreatic cancer. This technique offers a distinct advantage by allowing tissue stiffness measurements during the same procedure, thereby reducing the need for additional imaging studies and biopsies. Despite its clinical potential, challenges remain, including the need for standardized protocols, optimal cutoff values, and validation across diverse patient populations. This minireview provides a comprehensive analysis of the current literature on EUS-SWE, examining its diagnostic performance, reproducibility, and limitations. Furthermore, we discuss the future directions of EUS-SWE, including its integration into routine clinical practice and its evolving role in precision medicine, emphasizing the necessity of large-scale studies to solidify its clinical utility and establish standardized guidelines for its use.

Indexed as

Digestive SystemElasticity Imaging TechniquesEndosonographyGastrointestinal DiseasesHumansPrecision MedicineAutoimmune pancreatitisChronic pancreatitisEndoscopic ultrasoundLiver fibrosisShear wave elastography

Identifiers

PMID41479638
PMCPMC12754150

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.