ArticleFrontiers in neurology2025
Admission monocyte-to-albumin ratio predicts 3-month functional outcomes after acute ischemic stroke: a retrospective cohort study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of the CALLY index for functional outcomes in acute ischemic stroke: a systematic review and exploratory quantitative synthesis.Frontiers in neurology · 2026Pooled it
- The prognostic value of systemic inflammatory indices in elderly patients with spontaneous intracerebral hemorrhage.PloS one · 2026Observational
- Monocyte-to-Albumin Ratio (MAR) Is Associated With All-Cause Mortality in Adult Stroke Patients: Evidence From NHANES (1999-2018).Stroke research and treatment · 2026Article
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Authors and funding
5 authors.
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Abstract
Background: The monocyte-to-albumin ratio (MAR) integrates systemic inflammation and nutritional status derived from routine laboratory data. We assessed whether the admission MAR is associated with 3-month functional outcomes following acute ischemic stroke (AIS). Methods: We conducted a single-center, retrospective cohort study of consecutive adults with AIS admitted within 3 days of symptom onset (October 2023-March 2024). MAR was calculated from the admission monocyte counts and serum albumin levels. The primary outcome was poor 3-month functional status, defined as a modified Rankin Scale (mRS) score ≥3. Associations between MAR and outcomes were examined using multivariable logistic regression (with and without adjustment), smooth curve fitting, and prespecified subgroup analyses (sex, age, smoking status, drinking status, hypertension, diabetes status, eGFR, and TOAST subtype). Results: Among 395 patients (mean age 66.2 years; 34.7% female), 59 (14.9%) had poor outcomes. A higher admission MAR independently predicted poor outcomes: per 1-unit increase, the adjusted odds ratio (OR) was 1.13 (95% CI 1.07-1.20; Conclusion: The admission MAR is independently and positively associated with poor 3-month functional outcomes after AIS. MAR is a promising tool for early risk assessment when it is integrated with established predictors.
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