Evidence map›Paper›PMID 41479565›Full record

ArticleActa naturae

Targeted Radionuclide Detection of Malignant Tumors Using Affibody.

O D Bragina, A A Nesynov, E Yu Sitnikova, S V Patalyak, S M Deyev

Abstract read
In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

O D BraginaTomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, 634009 Russia.
A A NesynovTomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, 634009 Russia.
E Yu SitnikovaSiberian State Medical University, Tomsk, 634050 Russia.
S V PatalyakTomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, 634009 Russia.
S M DeyevNational Research Tomsk Polytechnic University, Tomsk, 634050 Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review examines the potential applications of affibody molecules in various fields of biotechnology and clinical medicine. Consideration is given to the high affinity and specificity of affibody molecules for selected molecular targets, as well as their potential for the in vivo visualization of various malignant tumors. Significant attention is paid to preclinical and clinical studies of affibody conjugates with various radioisotopes for targeted radionuclide tumor imaging, which is particularly relevant in addressing challenges encountered during the diagnosis and treatment of these patients. Clinical trials demonstrate that radiopharmaceuticals are well-tolerated and effective for the assessment of tumor process prevalence and the determination of HER2/neu status in breast cancer patients, supporting further research.

Indexed as

affibodiesalternative scaffold proteinsMalignant tumorstargeted radionuclide diagnosticstheranostics

Identifiers

PMID41479565
PMCPMC12755867

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.