Evidence map›Paper›PMID 41479432›Full record

ArticleClinical case reports2026

Sigmoid and Transverse Sinus Thrombosis as a Complication of Chronic Suppurative Otitis Media in a Child: A Case Report and Review of Literature.

Abdullah Nadeem, Hafiza Hafsa, Ruqaiya Shahid Raja, Mahad Shahid Raja, Muhammad Saad Abbas, Omer Javed Khan, Faisal Khalique, Riyan Imtiaz Karamat, Aymar Akilimali

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdullah NadeemDepartment of Medicine Dow University of Health Sciences Karachi Pakistan.ORCID https://orcid.org/0000-0002-1205-5426
Hafiza HafsaDow Medical College Karachi Pakistan.
Ruqaiya Shahid RajaShifa College of Medicine Islamabad Pakistan.
Mahad Shahid RajaAkhtar Saeed Medical College Lahore Pakistan.
Muhammad Saad AbbasAga Khan Medical College Karachi Pakistan.ORCID https://orcid.org/0000-0002-1796-5488
Omer Javed KhanCentral Park Medical College Lahore Pakistan.
Faisal KhaliqueLahore Medical and Dental College Lahore Pakistan.
Riyan Imtiaz KaramatRahbar Medical and Dental College Lahore Pakistan.ORCID https://orcid.org/0009-0000-1836-0459
Aymar AkilimaliDepartment of Research, Medical Research Circle (MedReC) Goma Democratic Republic of Congo.ORCID https://orcid.org/0000-0001-9393-1215

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic suppurative otitis media is an easily managed condition with potential for severe sinus thrombophlebitis complications secondary to cholesteatoma, if not diagnosed and treated promptly. Diagnosis relies on the culture and sensitivity of the drained suppuration, computed tomography (CT), and magnetic resonance imaging (MRI). Treatment entails a combination of all or some surgical, antibiotic, and anticoagulant use with postoperative follow-up. Our 8-year-old female patient presented with chronic left postauricular swelling with foul-smelling otorrhea and associated otalgia. More recently, she developed fever, headache, and vomiting. Fundoscopy noted papilledema. After ear examination, emergency incision and drainage were conducted with the suppuration sent for culture analysis. Tuberculosis was also ruled out. The patient had no history of dental caries. Contrast CT scan of the brain revealed features suggestive of partial thrombosis of the superior sagittal, left transverse sinus and sigmoid sinus extending up to the jugular vein. MRI and magnetic resonance venography (MRV) also indicated left otomastoiditis. Surgical treatment involved left-sided tympanomastoidectomy and otomastoidectomy. Anticoagulant Rivaroxaban was used 15 mg twice daily for 21 days. Postoperatively, the dosage was increased to 20 mg once daily for 3 months. Antibiotic vancomycin was administered preoperatively. Postoperative CT showed good prognosis. Postoperatively there was gradual improvement in headache and vision deterioration of right eye; fundoscopy showed improvement in papilledema, patient leukocyte counts also declined significantly, eventually to 13.4/μL. Anticoagulant and antibiotic therapy was continued. Some authors advocate only blood-brain barrier crossing antibiotics, while others employ surgical treatment. The risks involved with using anticoagulants must be carefully weighed before use. Our case presents classic clinical signs and symptoms.

Indexed as

antibioticanticoagulation managementchronic suppurative otitis mediacomplicationssigmoid sinus thrombosis

Identifiers

PMID41479432
PMCPMC12753295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.