MitomiRs as Key Players in Metabolic Reprogramming of Blood Cell Development.

Vijay Prasad Koppineedi, Mahesh Gutti, Bheriprasad Padhan, Amit Mishra, Ravi Kumar Gutti

Abstract readReview

In one paragraph

Review in Experientia supplementum (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

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2 · The registry

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Vijay Prasad KoppineediDepartment of Biochemistry, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad, India.

Mahesh GuttiK.V. Gachibowli, GPRA Campus Rd Indira Nagar, Gachibowli, Hyderabad, Telangana, India.

Bheriprasad PadhanDepartment of Biochemistry, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad, India.

Amit MishraDepartment of Bioscience & Bioengineering, Cellular and Molecular Neurobiology Unit, Indian Institute of Technology Jodhpur, Jodhpur, Rajasthan, India.

Ravi Kumar GuttiDepartment of Biochemistry, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are key players in regulating cellular metabolism. Short noncoding RNAs, or microRNAs (miRNAs), have become significant modulators of gene expression and cellular functions. Recent research has demonstrated the presence and activity of mitochondrial miRNAs (MitomiRs) in various cell types, including blood cells. The role of MitomiRNAs in metabolic reprogramming throughout blood cell formation, including their biosynthesis, function, and possible therapeutic implications, was discussed in this chapter. The discovery of mitochondrial microRNAs (MitomiRs) transformed our understanding of gene regulation in these critical organelles. These MitomiRs were discovered as they were influencing mitochondrial gene expression, with considerable effects on various cellular functions like oxidative stress responses, production of energy, and apoptosis during blood cell development.

Indexed as

Blood CellsMicroRNAsMitochondriaAnimalsApoptosisCellular ReprogrammingEnergy MetabolismGene Expression RegulationHumansMetabolic ReprogrammingOxidative StressMicroRNAsand Blood cell developmentHematopoietic stem cellsMetabolic reprogrammingMetabolismmiRNAsMitochondrial miRNA or mitomiRs

Identifiers

PMID41479119

DOI10.1016/j.omtn.2019.10.016

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