Evidence map›Paper›PMID 41479112›Full record

ReviewExperientia supplementum (2012)2026

Reconnaissance of the Good, the Bad, and the Ugly Role of tRNAs in Carcinogenesis and Metastasis.

Malik Ali Asghar, Mehraj Abbasov, Rukset Attar, Ammad Ahmad Farooqi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Experientia supplementum (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Malik Ali AsgharInstitute of Biomedical and Genetic Engineering (IBGE), Islamabad, Pakistan.
Mehraj AbbasovDepartment of Molecular Genetics and Genomics, Genetic Resources Institute of the Ministry of Science and Education of the Republic of Azerbaijan, Baku, Azerbaijan.
Rukset AttarDepartment of Obstetrics and Gynecology, Faculty of Medicine, Yeditepe University Hospital, Yeditepe University, Istanbul, Turkey.
Ammad Ahmad FarooqiInstitute of Biomedical and Genetic Engineering (IBGE), Islamabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our current knowledge of the translational mechanisms and the detailed structural insights of its components have highlighted the characteristically exclusive role of tRNAs and aminoacyl-tRNA synthetase diversity in the evolution of the genetic codes. Phenomenal advancements in mass spectrometry and high-throughput sequencing have enabled the researchers in developing a better understanding of the complex landscape of tRNA modifications. Emerging evidence has started to shed light on linchpin role of tRNAs in carcinogenesis and metastatic dissemination. In this chapter, we have provided an overview of the role of tRNAs, aminoacyl-tRNA synthetases, and tRNA-derived small RNAs in the onset and progression of cancer.

Indexed as

Amino Acyl-tRNA SynthetasesCarcinogenesisNeoplasmsRNA, TransferAnimalsGene Expression Regulation, NeoplasticHumansNeoplasm MetastasisAmino Acyl-tRNA SynthetasesRNA, TransferCarcinogenesisMetastasisNoncoding RNAtRNAs

Identifiers

PMID41479112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.