Evidence map›Paper›PMID 41479018›Full record

ArticleMolecular biology and evolution2026

MicrobeTrace 2.0: the enhanced visualization multitool for molecular epidemiology and bioinformatics.

Anupama Shankar, Evan Moscoso, David Cowan, Reagan Kelly, Roxana Cintron, Omar Ali Al-Naimi, William M Switzer

Abstract read
In one paragraph

Article in Molecular biology and evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anupama ShankarLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0003-4453-818X
Evan MoscosoGeneral Dynamics Information Technology, Atlanta, GA 30329, USA.ORCID 0009-0008-1132-8964
David CowanLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0002-4501-8437
Reagan KellyGeneral Dynamics Information Technology, Atlanta, GA 30329, USA.ORCID 0000-0002-5063-0655
Roxana CintronLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0002-0765-1186
Omar Ali Al-NaimiLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0009-0003-8798-2114
William M SwitzerLaboratory Branch, Division of HIV Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.ORCID 0000-0003-4591-8731

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicrobeTrace is a free, secure, browser-based bioinformatics tool to integrate and visualize epidemiologic, laboratory, and molecular data for outbreak investigations, with over 14,000 users from 127 countries. Regular testing, user feedback, and comparison with other bioinformatics tools identified areas for improvement, prompting major architectural and functional upgrades. In MicrobeTrace 2.0, we refactored the codebase using Angular to improve scalability, performance, and usability. We also replaced the D3.js visualization engine with Cytoscape.js for faster, more efficient rendering of large networks. The update adds enhanced visualizations, new analytical tools, and expanded functionality within existing views. It also supports seamless integration with external phylogenetic platforms, such as Nextstrain and UShER (Ultrafast Sample Placement on Existing Trees), enabling users to import phylogenetic trees, visualize them as genetic networks, and securely enrich them with epidemiological and demographic metadata. These enhancements position MicrobeTrace as a next-generation, interoperable tool for genomic epidemiology and data-driven public health response.

Indexed as

Computational BiologyMolecular EpidemiologySoftwareHumansPhylogenybioinformaticsdata analytics and visualizationmolecular epidemiologyoutbreak investigationsplatform interoperabilitysoftware

Identifiers

PMID41479018
PMCPMC12828226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.