Evaluation of Metabolic Characteristics of Cancer Cells.

Riddhi Mehta, Pritpal Kaur, Fatema Zohra Sadia, Patricia Maziarz, Ales Vancura

Abstract read

In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Riddhi MehtaDepartment of Biological Sciences, St. John's University, Queens, NY, USA.

Pritpal KaurDepartment of Biological Sciences, St. John's University, Queens, NY, USA.

Fatema Zohra SadiaDepartment of Biological Sciences, St. John's University, Queens, NY, USA.

Patricia MaziarzDepartment of Biological Sciences, St. John's University, Queens, NY, USA.

Ales VancuraDepartment of Biological Sciences, St. John's University, Queens, NY, USA. vancuraa@stjohns.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cells undergo a complex rearrangement of metabolic pathways that allows them to satisfy the needs of increased proliferation. Since many cancers are characterized by a high glycolytic rate regardless of oxygen availability, targeting glycolysis, electron transport chain (ETC), and oxidative phosphorylation (OXPHOS) have emerged as a potential therapeutic strategy. In this chapter, we describe a protocol that utilizes the Agilent Seahorse XFp Analyzer to assess mitochondrial respiration and glycolysis in ovarian cancer cells.

Indexed as

NeoplasmsOvarian NeoplasmsCell Line, TumorFemaleGlycolysisHumansMitochondriaOxidative PhosphorylationOxygen ConsumptionCancer metabolismExtracellular acidificationGlycolysisMitochondrial respirationOvarian cancerOxygen consumption rate

Identifiers

PMID41478976

DOI10.1007/978-1-0716-0247-8_17

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.