ArticleMethods in molecular biology (Clifton, N.J.)2026
Use of Biomimetic Hydrogels and 3D Cancer Models for Biochemical and Cell Biological Assays.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Sequential invasion assays identify carbonic anhydrase IX as a driver of invasiveness in epithelial triple-negative breast cancer cells.American journal of physiology. Cell physiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many different cell types including stem cells, cancer cells, and cells of the immune system use cell-to-cell and cell-to-extracellular matrix interactions to communicate and to move in space, behaviors that are crucial to their physiological and pathophysiological properties. While conventionally two-dimensional (2D) cell culture was used to study these cellular phenomena, complex three-dimensional (3D) environments more truthfully reflect the biochemical and biomechanical properties of the extracellular matrix and allow analysis of cellular functions under physiologically relevant conditions. Here, we present protocols to study individual cells as well as multicellular cell aggregates within a 3D collagen type I matrix that is amenable to microscopy-based analysis. This approach facilitates analyses of migratory behaviors, reciprocal cell-cell and cell-ECM interactions as well as subcellular distributions of proteins of interest in physiologically relevant 3D settings.
Indexed as
Identifiers
41478973What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.