Evidence map›Paper›PMID 41478958›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Single-Cell Low-Pass Whole Genome Sequencing of Circulating Tumor Cells.

Zhuo Wang, Qihui Shi

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhuo WangInstitutes of Biomedical Sciences, Fudan University, Shanghai, China.
Qihui ShiInstitutes of Biomedical Sciences, Fudan University, Shanghai, China. qihuishi@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-cell whole genome sequencing (WGS) enables accurate identification and characterize circulating tumor cells (CTCs) in blood and non-blood body fluids, leading to a non- or minimally invasive liquid biopsy approach for cancer diagnosis and prognosis. Here, we describe a single-cell low-pass WGS protocol for sensitive and accurate CTCs detection in blood and non-blood body fluids by combining a metabolic function-associated marker and a Tn5 transposome-based WGS method.

Indexed as

NeoplasmsNeoplastic Cells, CirculatingSingle-Cell AnalysisWhole Genome SequencingBiomarkers, TumorHigh-Throughput Nucleotide SequencingHumansLiquid BiopsyBiomarkers, TumorCirculating tumor cellsCopy number alterationSingle-cell sequencingWhole genome sequencing

Identifiers

PMID41478958

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.