Evidence map›Paper›PMID 41478951›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Accelerating Genomics: Innovations in Analyzing Limited and Rare Samples.

Ioanna Andreou, Markus Storbeck, Jonathan Schaffer

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ioanna AndreouQIAGEN GmbH, Hilden, Germany. ioanna.andreou@qiagen.com.
Markus StorbeckQIAGEN GmbH, Hilden, Germany.
Jonathan SchafferQIAGEN Inc., Frederick, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-cell genomic analysis offers insights into various biological fields but is challenged by the limited DNA from single cells. Whole genome amplification (WGA) techniques, such as PCR and multiple displacement amplification (MDA), facilitate the creation of high-quality next-generation sequencing (NGS) libraries. Advances in sequencing technologies and enrichment methods have reduced costs and enabled the analysis of a significant number of single cells. Effective cell isolation techniques maintain cell viability and integrity. This article presents a streamlined workflow that includes single-cell dispensing, genome amplification, and NGS library generation.

Indexed as

GenomicsHigh-Throughput Nucleotide SequencingSingle-Cell AnalysisGene LibraryHumansNucleic Acid Amplification TechniquesPolymerase Chain ReactionSequence Analysis, DNAWorkflowCell isolationHybrid captureMDANGSPCRSingle cell genomicsWGA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.