Evidence map›Paper›PMID 41478937›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Quantitative In Vitro and In Vivo Assays to Assess the Efferocytic Efficiency of Macrophages.

Eduardo Gutseit, Vinícius Amorim Beltrami, Débora Gonzaga Martins, Mauro Martins Teixeira, Lirlândia Pires de Sousa, Juliana Priscila Vago, Vanessa Pinho, Franciel Batista Felix

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eduardo GutseitDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.ORCID https://orcid.org/0000-0002-6149-8450
Vinícius Amorim BeltramiDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.ORCID https://orcid.org/0009-0008-7365-0916
Débora Gonzaga MartinsDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.ORCID https://orcid.org/0000-0001-7853-3809
Mauro Martins TeixeiraDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.ORCID https://orcid.org/0000-0002-6944-3008
Lirlândia Pires de SousaDepartamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.ORCID https://orcid.org/0000-0002-1042-9762
Juliana Priscila VagoDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.ORCID https://orcid.org/0000-0001-8188-3738
Vanessa PinhoDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.ORCID https://orcid.org/0000-0003-1038-2324
Franciel Batista FelixDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte-MG, Brazil.ORCID https://orcid.org/0000-0002-2372-2781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efferocytosis is a process in which specialized phagocytes, mainly macrophages, are responsible for recognizing and removing apoptotic cells from the inflammatory site, leading to tissue resolution, and preventing chronic inflammation. Herein we describe in detail a robust efferocytosis assay based on morphological criteria and flow cytometric for the quantification of efferocytic events and characterization of the engulfing efficiency of apoptotic cells by macrophage in vitro and in vivo, which can be used in many applications, including the development of genetic and pharmacological therapeutic targeting inflammation resolution.

Indexed as

ApoptosisMacrophagesPhagocytosisAnimalsFlow CytometryHumansInflammationMiceApoptosisEfferocytosisFlow cytometryInflammation resolutionMacrophages

Identifiers

PMID41478937

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.