Evidence map›Paper›PMID 41478917›Full record

ReviewAdvances in experimental medicine and biology2026

Impact of Prenatal Alcohol Exposure on the Cerebral Circulation: Potential Implications for Stroke.

Partha S Saha, Denise M Arrick, William G Mayhan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Partha S SahaSchool of Science, Technology, Engineering, and Math (STEM), Diné College, Shiprock, NM, USA.
Denise M ArrickDivision of Biomedical and Translational Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD, USA.
William G MayhanDivision of Biomedical and Translational Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD, USA. william.mayhan@usd.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal alcohol exposure (PAE) is recognized as a teratogenic factor that affects neural development, resulting in a range of structural, functional, and cognitive/behavioral abnormalities contributing to the pathogenesis of fetal alcohol spectrum disorder (FASD). FASD is a major preventable cause of developmental delay in humans. There are many molecular and cellular mechanisms by which PAE could contribute to abnormalities seen in individuals with FASD. Understanding these mechanisms will be critical for the development of therapeutic approaches that could benefit not only the developing fetus, but the newborn as they mature into adolescence and adulthood. The goal of this review is to discuss the impact of PAE on neural and vascular development/function and define potential cellular/molecular mechanisms that contribute to the effects of PAE. We believe that an understanding regarding the influence of PAE on cerebral vascular function may provide insights into the pathogenesis of symptoms related to FASD.

Indexed as

Cerebrovascular CirculationEthanolFetal Alcohol Spectrum DisordersPrenatal Exposure Delayed EffectsStrokeAlcohol DrinkingAnimalsBrainFemaleHumansPregnancyEthanolMicrocirculationNitric oxideOxidative stressReactivity

Identifiers

PMID41478917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.