ArticleMethods in molecular biology (Clifton, N.J.)2026
Couette Flow Linear Dichroism Spectroscopy.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- RNAs Associated With Bacterial Outer Membrane Vesicles: Structural Insights Into Surface Composition.Journal of extracellular vesicles · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Linear Dichroism (LD) spectroscopy uses linearly polarized light to measure how a molecule orients itself with respect to a reference axis or, more precisely, how the transition moment of a chromophore in the molecule is oriented. This provides insight into how, e.g., molecules assemble into macromolecules and their orientation with respect to each other. Prerequisites for LD is a medium in which the molecules orient in a preferred direction and that the molecules under investigation are long enough to allow orientation. For long biomolecules such as RNA/DNA or fibrils of proteins in solution, Couette flow is an efficient way of creating a flow-induced orientation of the molecules, while recirculating a small volume of sample. In this chapter, we present the methodology behind LD spectroscopy including best practice for sample handling and data collection, as well as the interpretation of LD spectra including examples of RNA, DNA, proteins, and their complexes.
Indexed as
Identifiers
41478903What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.