Evidence map›Paper›PMID 41478900›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

The Nucleic Acids Circular Dichroism and Fourier Transform Databases NACDDB and NAIRDB: New Tools for RNA Structural Analysis.

Kevin Mosca, Elsa Balduzzi, Dominik Sordyl, Andrea Cappannini, Frédéric Geinguenaud, Frank Wien, Véronique Arluison, Janusz M Bujnicki

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Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevin Mosca *Laboratoire Léon Brillouin LLB, CEA, CNRS UMR 12, CEA Saclay, Gif-sur-Yvette, France.
Elsa Balduzzi *Laboratoire Léon Brillouin LLB, CEA, CNRS UMR 12, CEA Saclay, Gif-sur-Yvette, France.
Dominik SordylLaboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.
Andrea CappanniniLaboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.
Frédéric GeinguenaudLaboratory for Vascular Translational Science, LVTS, UMR 1148, Université Sorbonne Paris Nord, UFR SMBH, Bobigny, France.
Frank WienSynchrotron SOLEIL, L'Orme des Merisiers, Départementale 128, Gif-sur-Yvette, France. frank.wien@synchrotron-soleil.fr.
Véronique ArluisonLaboratoire Léon Brillouin LLB, CEA, CNRS UMR 12, CEA Saclay, Gif-sur-Yvette, France. Veronique.arluison@u-paris.fr.ORCID https://orcid.org/0000-0003-4056-7282
Janusz M BujnickiLaboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland. janusz@iimcb.gov.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fourier Transform Infrared (FTIR) and Circular Dichroism (CD) spectroscopies are powerful and rapid techniques that provide valuable insights into the conformational properties of nucleic acids (NA). These spectroscopic methods, sensitive to vibrational and electronic absorption, can detect subtle changes in the molecular structure of nucleic acids. In this chapter, we introduce two new spectroscopic databases, NACDDB and NAIRDB, which offer a comprehensive collection of CD and IR datasets for various nucleic acid molecules, including many RNAs. Entries in NACDDB and NAIRDB are linked to primary sequences, experimental structural data, relevant literature references, and, when available, 3D structures or models. These two databases serve as valuable resources for researchers, facilitating their study of nucleic acid conformations and enhancing their understanding of NA structural dynamics.

Indexed as

Circular DichroismDatabases, Nucleic AcidRNADatasets as TopicNucleic Acid ConformationRNA FoldingSoftwareSpectroscopy, Fourier Transform InfraredRNABase stacking and pairingChiro-optical spectroscopyHelical propertiesSugar pucker, RNA secondary structure, Spectroscopic databaseVibrational spectroscopy

Identifiers

PMID41478900

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.