Evidence map›Paper›PMID 41478898›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

FAMP: A Software Framework for FRET-Based Integrative Modeling of RNA.

Felix Erichson, Fabio D Steffen, Richard Börner

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. FRET-guided selection of RNA 3D structures.Nucleic acids research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Felix ErichsonLaserinstitut Hochschule Mittweida, Mittweida University of Applied Sciences, Mittweida, Germany.
Fabio D SteffenDepartment of Oncology, University Children's Hospital, University of Zurich, Zurich, Switzerland.
Richard BörnerLaserinstitut Hochschule Mittweida, Mittweida University of Applied Sciences, Mittweida, Germany. richard.boerner@hs-mittweida.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrative biomolecular modeling uses experimental data to validate computationally generated structures. We use Förster-Resonance-Energy transfer (FRET) as an experimental distance measure on the molecular level to evaluate de novo predicted ribonucleic acid (RNA) 3D structure collections. FRET-assisted RNA structure prediction requires an intricate interplay of multiple software components. It involves generating an initial RNA 3D model, performing in silico fluorophore labeling, and computing FRET observables from molecular dynamics (MD) trajectories. To automate this workflow, we developed a Python-based computational pipeline that integrates FRET as an experimental constraint for RNA structure validation.

Indexed as

Computational BiologyFluorescence Resonance Energy TransferRNASoftwareMolecular Dynamics SimulationNucleic Acid ConformationRNAFAMPFRET predictionsIntegrative modelingRNA 3D structuresSingle-molecule FRET (smFRET)

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.