Evidence map›Paper›PMID 41478883›Full record

ReviewNature reviews. Cardiology2026

Tricuspid valve disease: updates on diagnostic imaging and intervention.

Julia Grapsa, Edoardo Zancanaro, Karl Philipp Rommel, Lukas Weber, Augustin Coisne, Rodrigo Estevez-Loureiro, Victoria Delgado, Marta Sitges, Maurice Enriquez-Sarano, Fabien Praz and 10 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Julia GrapsaHeart and Vascular Institute, Brigham and Women's Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA. igrapsa@bwh.harvard.edu.ORCID http://orcid.org/0000-0003-4620-6234
Edoardo ZancanaroHeart and Vascular Institute, Brigham and Women's Hospital, Mass General Brigham, Harvard Medical School, Boston, MA, USA.
Karl Philipp RommelDepartment of Cardiac and Vascular Surgery, University of Mainz, Faculty of Medicine and University Hospital Mainz, Mainz, Germany.
Lukas WeberHôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France.
Augustin CoisneUniversity of Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.
Rodrigo Estevez-LoureiroDepartment of Cardiology, University Hospital Alvaro Cunqueiro, Vigo, Spain.
Victoria DelgadoHeart Institute, Department of Cardiology, Germans Trias i Pujol University Hospital, Barcelona, Spain.
Marta SitgesCardiovascular Institute, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0003-1300-4732
Maurice Enriquez-SaranoMinneapolis Heart Institute, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0003-0910-5450
Fabien PrazUniversitätsklinik Für Kardiologie, Inselspital Bern, Bern, Switzerland.
Neil FamSt. Micheal's Hospital, Toronto, Ontario, Canada.
Nicole CristellCardiovascular Research Foundation, New York, NY, USA.
Azeem LatibMontefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
Nicolo PiazzaMcGill University Health Centre, Montreal, Quebec, Canada.
Philipp LurzDepartment of Cardiology, University Medical Center Mainz, Mainz, Germany.
Thomas ModineHôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux, France.
Jörg HausleiterMedizinische Klinik und Poliklinik I, LMU Klinikum, LMU München, Munich, Germany.
Rebecca T HahnCardiovascular Research Foundation, New York, NY, USA.ORCID http://orcid.org/0000-0003-1342-9191
Martin B LeonNewYork-Presbyterian/Columbia University Medical Center, New York, NY, USA.
Juan F GranadaCardiovascular Research Foundation, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tricuspid regurgitation is associated with an increased risk of hospitalization and death. Many patients with severe tricuspid regurgitation are unable to undergo surgical intervention owing to prohibitive technical or clinical risk. The past two decades has seen an outburst of technological advances in the field of transcatheter tricuspid technologies, with numerous randomized, controlled trials assessing the safety and efficacy of various repair and replacement therapies for tricuspid regurgitation. However, crucial knowledge gaps persist, particularly in areas such as patient selection, anatomical eligibility and the haemodynamic effects of device implantation. In this Review, we outline the anatomical features of the tricuspid valve and the haemodynamic consequences of tricuspid regurgitation, and we summarize the imaging modalities used for diagnosis and management. Furthermore, we detail the current guideline-directed medical therapy for tricuspid regurgitation, as well as valve repair and replacement surgical procedures being tested in clinical trials. Finally, we highlight future technological innovations that promise to optimize diagnosis, patient selection and the device development process.

Indexed as

Heart Valve Prosthesis ImplantationTricuspid ValveTricuspid Valve InsufficiencyCardiac CatheterizationHeart Valve ProsthesisHemodynamicsHumansPatient SelectionPredictive Value of TestsTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.