Evidence map›Paper›PMID 41478876›Full record

ReviewNature reviews. Molecular cell biology2026

Advancing single-cell omics and cell-based therapeutics with quantum computing.

Aritra Bose, Kahn Rhrissorrakrai, Filippo Utro, Laxmi Parida, Quantum for Healthcare Life Sciences Consortium

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Molecular cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Remics: a redescription-based framework for multi-omics analysis.Frontiers in cell and developmental biology · 2026
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Aritra BoseIBM Research, Yorktown Heights, NY, USA.ORCID http://orcid.org/0000-0002-8665-056X
Kahn RhrissorrakraiIBM Research, Yorktown Heights, NY, USA.ORCID http://orcid.org/0000-0002-1567-9090
Filippo UtroIBM Research, Yorktown Heights, NY, USA.ORCID http://orcid.org/0000-0003-3226-7642
Laxmi ParidaIBM Research, Yorktown Heights, NY, USA. parida@us.ibm.com.ORCID http://orcid.org/0000-0002-7872-5074
Quantum for Healthcare Life Sciences Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The generation of highly accurate models of behaviours of individual cells and cell populations through integration of high-resolution assays with advanced computational tools would transform precision medicine. Recent breakthroughs in single-cell and spatial transcriptomics and multi-omics technologies, coupled with artificial intelligence, are driving rapid progress in model development. Complementing the advances in artificial intelligence, quantum computing is maturing as a novel compute paradigm that may offer potential solutions to overcome the computational bottlenecks inherent to capturing cellular dynamics. In this Roadmap article, we discuss the advancements and challenges in spatiotemporal single-cell analysis, explore the possibility of quantum computing to address the challenges and present a case study on how quantum computing may be integrated into cell-based therapeutics. The specific confluence of quantum and classical computing with high-resolution assays may offer a crucial path towards the generation of transformative models of cellular behaviours and perturbation responses.

Indexed as

Cell- and Tissue-Based TherapyComputational BiologyGenomicsQuantum TheorySingle-Cell AnalysisAnimalsArtificial IntelligenceHumans

Identifiers

PMID41478876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.