Evidence map›Paper›PMID 41478156›Full record

ArticleColloids and surfaces. B, Biointerfaces2026

Vibrio choleraeadhesin-derived peptides mediate strong pull-off forces in aqueous media with high ionic strength.

Syeda Tajin Ahmed, Sixin Zhai, Xin Huang, Sarvagya Sulaja, Adekunle Adewole, Alisa Ioffe, Andrea D Merg, Jing Yan, Roberto C Andresen Eguiluz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Colloids and surfaces. B, Biointerfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. A biofilm-derived peptide as an underwater adhesive.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

  • Update of
    2025
5 · Who and what money

Authors and funding

9 authors.

Syeda Tajin AhmedDepartment of Chemical and Materials Engineering, University of California, Merced, Merced, CA 95344, USA.
Sixin ZhaiMaterials and Biomaterials Science and Engineering Graduate Group, University of California Merced, Merced, CA 95344, USA.
Xin HuangDepartment of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT 06511, USA.
Sarvagya SulajaDepartment of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT 06511, USA.
Adekunle AdewoleChemistry and Biochemistry Graduate Group, University of California Merced, Merced, CA 95344, USA.
Alisa IoffeDepartment of Chemistry and Biochemistry, University of California Merced, Merced, CA 95344, USA.
Andrea D MergMaterials and Biomaterials Science and Engineering Graduate Group, University of California Merced, Merced, CA 95344, USA; Department of Chemistry and Biochemistry, University of California Merced, Merced, CA 95344, USA.
Jing YanDepartment of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT 06511, USA; Quantitative Biology Institute, Yale University, New Haven, CT 06511, USA.
Roberto C Andresen EguiluzDepartment of Chemical and Materials Engineering, University of California, Merced, Merced, CA 95344, USA; Materials and Biomaterials Science and Engineering Graduate Group, University of California Merced, Merced, CA 95344, USA; Health Sciences Research Institute, University of California Merced, Merced, CA 95344, USA. Electronic address: randreseneguiluz@ucmerced.edu.

Funding

G-RISE at UC MercedT32GM141862 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI GOPINATHAN, AJAY, LIWANG, ANDY · 2021 to 2025
$2.7M
Tracking single-cell gene expression heterogeneity and its consequences in bacterial biofilmsDP2GM146253 · NIGMS · YALE UNIVERSITY · PI YAN, JING · 2021 to 2024
$2.5M
NIGMS NIH HHS DP2 GM146253NIGMS NIH HHS T32 GM141862
6 · The paper itself

Abstract

In this study, the pull-off forces of adsorbed films of four Bap1-inspired peptides in various solvents were investigated on negatively charged mica substrates using the surface forces apparatus (SFA), complemented with dynamic light scattering (DLS) for characterizing the aggregation behavior of peptides in solution. Bap1-inspired peptides consisted of the 57 amino acid wild-type sequence (WT); a scrambled version of the WT used to investigate the impact of the primary amino acid sequence in pull-off forces (Scr); a ten amino acid sequence rich in hydrophobic content (CP) of the WT sequence, and an eight amino acid sequence (Sh1) that corresponds to the pseudo-repeating sequence in the 57 AA. SFA results showed remarkable pull-off forces for CP, particularly in the presence of salts: measured pull-off forces were 26.0 ± 7.0 mN/m for no dwell-time and up to 42.0 ± 8.8 mN/m when surfaces were left in contact for 30 min. Sh1 did not bridge mica surfaces, while large aggregates clouded SFA measurements of Scr. DLS observations indicated that salts favored large peptide aggregation for all constructs (D

Indexed as

PeptidesVibrio choleraeWaterAluminum SilicatesAmino Acid SequenceHydrophobic and Hydrophilic InteractionsOsmolar ConcentrationSurface PropertiesAluminum SilicatesmicaPeptidesWaterbacteria-inspired adhesionSurface Forces ApparatusVibrio choleraewet adhesion

Identifiers

PMID41478156
PMCPMC13568590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.