Evidence map›Paper›PMID 41477864›Full record

ArticleScience advances2026

Lost and found: Rediscovering microbiome-associated phenotypes that reshape agricultural sustainability.

Alonso Favela, Angela D Kent, Connor N Sible, Sherry Flint-Garcia, Isaac M Klimasmith, Christopher Mujjabi, Sierra S Raglin, Fred E Below, Martin O Bohn

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alonso FavelaSchool of Plant Sciences, University of Arizona, Tucson, AZ 85721, USA.ORCID 0000-0001-7743-1149
Angela D KentProgram in Ecology, Evolution, and Conservation Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0003-1837-2382
Connor N SibleDepartment of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0009-0003-2096-3533
Sherry Flint-GarciaUSDA-ARS, Columbia, MO 65211, USA.
Isaac M KlimasmithDepartment of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Christopher MujjabiDepartment of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0009-0000-6273-0672
Sierra S RaglinDepartment of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-9580-5714
Fred E BelowDepartment of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-7696-3688
Martin O BohnDepartment of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0003-2364-6229

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern agriculture faces an urgent need to improve nutrient use efficiency while reducing environmental impacts. Here, we show that ancestral traits controlling rhizosphere microbiome functions can be reintroduced into elite maize through targeted teosinte introgressions. Using near-isogenic lines, we mapped microbiome-associated phenotypes (MAPs) derived from teosinte that suppress nitrification and denitrification-key microbial processes contributing to nitrogen loss. These introgressions altered root exudate chemistry, resulting in distinct microbial assemblies and enhanced nitrogen retention. We identified candidate loci and exudate metabolites responsible for suppressive activity and demonstrated their functional effects in vitro. These findings reveal a genetic and biochemical basis for rewilding microbiome-mediated ecosystem services in crops, offering a scalable path toward sustainable nutrient management in global agriculture.

Indexed as

AgricultureMicrobiotaZea maysCrops, AgriculturalNitrificationNitrogenPhenotypePlant RootsRhizosphereSoil MicrobiologyNitrogen

Identifiers

PMID41477864
PMCPMC12757070

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.