Evidence map›Paper›PMID 41477707›Full record

ReviewACS nano2026

Magnetic Field-Driven Strategies for Biofilm Disruption: From Iron Oxide Nanoparticles to Adaptive Swarms of Magnetic Microrobots.

Maja Caf, Parvaneh Esmaeilnejad-Ahranjani, Jelena Kolosnjaj-Tabi, Jerica Sabotič, Aleš Berlec, Nika Zaveršek, Stane Pajk, Abida Zahirović, Muriel Golzio, Irena Milosevic and 1 more

Abstract readReview
In one paragraph

Review in ACS nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maja CafDepartment for Materials Synthesis, Jožef Stefan Institute, Ljubljana 1000, Slovenia.
Parvaneh Esmaeilnejad-AhranjaniDepartment for Materials Synthesis, Jožef Stefan Institute, Ljubljana 1000, Slovenia.
Jelena Kolosnjaj-TabiInstitut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III-Paul Sabatier (UPS), Toulouse 31400, France.
Jerica SabotičDepartment of Biotechnology, Jožef Stefan Institute, Ljubljana 1000, Slovenia.ORCID 0000-0002-2404-0192
Aleš BerlecFaculty of Pharmacy, University of Ljubljana, Ljubljana 1000, Slovenia.ORCID 0000-0002-8095-6998
Nika ZaveršekDepartment of Biotechnology, Jožef Stefan Institute, Ljubljana 1000, Slovenia.
Stane PajkFaculty of Pharmacy, University of Ljubljana, Ljubljana 1000, Slovenia.
Abida ZahirovićDepartment of Biotechnology, Jožef Stefan Institute, Ljubljana 1000, Slovenia.
Muriel GolzioInstitut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III-Paul Sabatier (UPS), Toulouse 31400, France.
Irena MilosevicHEPIA, University of Applied Sciences of Western Switzerland (HES-SO), Geneva 1202, Switzerland.
Slavko KraljDepartment for Materials Synthesis, Jožef Stefan Institute, Ljubljana 1000, Slovenia.ORCID 0000-0002-0771-3818

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilms, structured communities of microbial cells embedded in extracellular polymeric substances, are notorious for their resilience against conventional antimicrobial treatments. They contribute significantly to chronic infections and industrial biofouling, necessitating innovative strategies for their eradication. Magnetic iron oxide nanoparticles have emerged as a promising tool in combating biofilms due to their biocompatibility and unique physicochemical properties, which enable magnetic delivery of antibacterial agents, magnetic hyperthermia, magneto-mechanical actuation including mechanical biofilm disruption, and reversible dynamic magnetic assembly into hierarchical structures. This review describes developing stages of magnetic nanoscale weapons against biofilms ranging from individual iron oxide nanoparticles to complex hierarchical nanoparticle assemblies in the form of magnetic robots and their swarms. A vast array of possible antibiofilm and antibacterial functionalities originating from iron ions, individual iron oxide nanoparticles, spherical nanoparticle assemblies, magnetic robots, and swarms of robots are presented. Magnetic nanotools offer significant improvements and advantages over conventional methods for biofilm eradication, yet their successful future applications depend on addressing and overcoming critical material, biological, and engineering challenges.

Indexed as

Anti-Bacterial AgentsBiofilmsMagnetic FieldsMagnetic Iron Oxide NanoparticlesRoboticsHumansAnti-Bacterial Agentsantibiotic resistancebiofilm eradicationmagnetic microrobot swarmsmagnetic nanoparticlesmagneto-mechanical actuationmicrorobotic superstructuresmicrorobotsnanorobotsSPIONs

Identifiers

PMID41477707
PMCPMC12810490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.