Evidence map›Paper›PMID 41477629›Full record

ReviewFood chemistry: X2025

Metabolomic-based promising technique for fruit-based natural products analysis.

Abdur Rauf, Ahmed Olatunde, Zuneera Akram, Hassan A Hemeg, Anees Ahmed Khalil, Mohammad Ali Shariati, Zehra Edis, Muthu Thiruvengadam, Seung-Hyun Kim

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdur RaufDepartment of Chemistry, University of Swabi, Swabi, Anbar, 94640, Khyber Pakhtunkhwa, Pakistan.
Ahmed OlatundeDepartment of Medical Biochemistry, Abubakar Tafawa Balewa University, Bauchi 740272, Nigeria.
Zuneera AkramDepartment of Pharmacology, Faculty of Pharmaceutical Sciences, Baqai Medical University, Karachi, 75340, Pakistan.
Hassan A HemegDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Saudi Arabia.
Anees Ahmed KhalilUniversity Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, 54000, Pakistan.
Mohammad Ali ShariatiKazakh Research Institute of Processing and Food Industry, Semey Branch of the Institute, 238«G» Gagarin Ave., Almaty, 050060, Republic of Kazakhstan.
Zehra EdisCenter of Medical and Bio-Allied Health Sciences Research, Ajman University, United Arab Emirates.
Muthu ThiruvengadamDepartment of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul, 05029, Republic of Korea.
Seung-Hyun KimDepartment of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul, 05029, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fruit-based natural products have significant health and commercial benefits. Liquid chromatography-high-resolution mass spectrometry (LC-HRMS) is a powerful technique to profile complex chemical compositions. This review focuses on the use of LC-HRMS for profiling fruit-derived bioactive chemicals and demonstrates the advantages of LC for separation and HRMS for precise mass detection. LC-HRMS enables the detection of a wide range of bioactive compounds, while providing excellent precision and resolution, allowing distinction between isomeric and isobaric compounds and advancing the understanding of fruit metabolomes and their roles in food and pharmaceutical sciences. Although challenges such as complex sample preparation and limited databases persist, LC-HRMS continues to be the leading method for discovering novel bioactive compounds. Continuous improvements in analytical procedures and data resources are required to fully realize the potential of LC-HRMS. Overall, the integration of LC and HRMS has altered fruit-based analyses of natural products, providing their chemical profiles and encouraging innovations in health-related and industrial applications.

Indexed as

BioactivesChemical profilingLiquid chromatography-High resolution mass spectrometryNatural products

Identifiers

PMID41477629
PMCPMC12752530

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.