Evidence map›Paper›PMID 41477551›Full record

ArticleMolecular therapy. Oncology2025

Evaluation of dasatinib and ponatinib for the control of CD123 CAR-T cell functionalities.

Charles-Frédéric Mantion, Sabeha Biichlé, Xavier Roussel, Gwenaël Rolin, Agathe Lejeune, Tony Labaigt, Elodie Bôle-Richard, Etienne Daguindau, Bernard Royer, Florian Renosi and 4 more

Abstract read
In one paragraph

Article in Molecular therapy. Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Charles-Frédéric MantionUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Sabeha BiichléUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Xavier RousselUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Gwenaël RolinUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Agathe LejeuneUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Tony LabaigtUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Elodie Bôle-RichardFC' Innov, Bionoveo, 25000 Besançon, France.
Etienne DaguindauUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Bernard RoyerUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Florian RenosiUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Olivier AdoteviUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Romain LoyonUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Maxime FredonUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.
Francine Garnache-OttouUniversité Marie et Louis Pasteur, EFS, INSERM, RIGHT (UMR 1098), 25000 Besançon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD123 CAR-T cells (CAR123) represent a promising therapeutic approach for blastic plasmacytoid dendritic cell neoplasm (BPDCN) and CD123

Indexed as

AMLBPDCNCAR-T cellCD123dasatinibendothelial cellMT: Regular Issueponatinibtoxicity

Identifiers

PMID41477551
PMCPMC12752794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.