Evidence map›Paper›PMID 41477535›Full record

ArticleOpen forum infectious diseases2026

Assessment of RNA at SVR4 and Treatment Completion as Alternative Measures of Hepatitis C Cure for People Who Inject Drugs.

Claire McDonell, Ryan Assaf, Jeff McKinney, David Glidden, Annie Luetkemeyer, Brittney Ayala, Jaline Chan, Jennifer C Price, Meghan D Morris

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claire McDonellDepartment of Epidemiology and Biostatistics, University of California, San Francisco (UCSF), San Francisco, California, USA.ORCID https://orcid.org/0009-0005-7116-3346
Ryan AssafDivision of Health Equity and Society, Department of Medicine, UCSF, San Francisco, California, USA.ORCID https://orcid.org/0000-0002-6651-1765
Jeff McKinneyDepartment of Medicine, UCSF, San Francisco, California, USA.
David GliddenDepartment of Epidemiology and Biostatistics, University of California, San Francisco (UCSF), San Francisco, California, USA.
Annie LuetkemeyerDepartment of Medicine, UCSF, San Francisco, California, USA.
Brittney AyalaDepartment of Epidemiology and Biostatistics, University of California, San Francisco (UCSF), San Francisco, California, USA.
Jaline ChanDepartment of Epidemiology and Biostatistics, University of California, San Francisco (UCSF), San Francisco, California, USA.
Jennifer C PriceDepartment of Medicine, UCSF, San Francisco, California, USA.
Meghan D MorrisDepartment of Epidemiology and Biostatistics, University of California, San Francisco (UCSF), San Francisco, California, USA.ORCID https://orcid.org/0000-0003-2762-2953

Funding

Harnessing interpersonal connections for improved patient-oriented research for people who inject drugs (PWID)K24DA061103 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Meghan D Morris · 2025 to 2026
$433k
NIDA NIH HHS K24 DA061103
6 · The paper itself

Abstract

Hepatitis C virus treatment guidance was updated to include sustained virologic response at 4-weeks post-treatment (SVR4) as an alternative measure of cure for select groups. Among a community-based sample of people who inject drugs receiving an accelerated test-and-treat protocol, results at treatment completion and SVR4 predicted those at 12-week post-treatment.

Indexed as

direct-acting antiviralsdrug usepositive predictive valueviral hepatitis

Identifiers

PMID41477535
PMCPMC12750323

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.