ArticleOpen forum infectious diseases2026
Normalization of Seasonality and Age Distribution of Pediatric RSV Infection Following the Pandemic Disruption in the Netherlands.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Regional inequality in infant RSV morbidity and mortality burden in the era of expanded RSV passive immunisation: a global projection modelling study.EClinicalMedicine · 2026Article
- Respiratory Infection-Related Pathogens in the Pediatric Intensive Care Unit During 2019-2024 in Hubei, China.Pathogens (Basel, Switzerland) · 2026Article
- Epidemiology of human RSV in Taiwan, 2018-2024.PloS one · 2026Article
- A Predictive Nomogram for Severe RSV Infection in Children: A Retrospective, Single-Center Development and Validation Study.Journal of inflammation research · 2026Article
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Authors and funding
9 authors.
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Abstract
Background: The COVID-19 pandemic caused a global disruption in respiratory syncytial virus (RSV) epidemiology. However, data on RSV epidemiology in the postpandemic period remain limited. We analyzed shifts in RSV seasonality, age distribution, and disease severity among RSV-positive children in the Netherlands before, during, and after the pandemic. Methods: Between May 2021 and April 2024, children under two years of age, admitted with RSV to 47 Dutch hospitals were included in a prospective surveillance study. We compared demographic and clinical characteristics of RSV-positive patients with data from the pre-COVID period (2018-2020), the COVID period and the post-COVID period (2022-2024). Results: A total of 8457 RSV-positive cases were included, with detailed data collected from 2708 patients (13 hospitals). Following an unusual off-season shift and a period of endemic circulation, RSV seasonality has reverted to its typical prepandemic winter pattern. The median age at admission increased from 2.2 months (interquartile range [IQR]: 1.1-5.6) in the prepandemic period to 4.9 months (IQR 1.8-11.4, Conclusions: The COVID-19 pandemic profoundly disrupted RSV epidemiology. This prospective study demonstrates a rapid re-establishment of prepandemic patterns, including a return toward the typical age distribution during early childhood.
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