ArticleCureus2025
Early Histiocytic Pleuritis Revealing Tuberculosis on Repeat Thoracoscopy: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculosis (TB) continues to pose a global health challenge, particularly in its extrapulmonary forms such as pleural and pericardial involvement. These presentations often mimic other conditions and yield inconclusive results on initial microbiological and histopathological testing due to their paucibacillary nature. We report the case of a 45-year-old previously healthy man who presented with recurrent pleural and pericardial effusions. Extensive investigations during the first admission, including pleural fluid analysis, polymerase chain reaction (PCR), and thoracoscopic biopsy, were non-diagnostic. Histopathology initially revealed chronic histiocytic inflammation without necrosis, a finding frequently considered nonspecific but which may represent an early stage of tuberculous pleuritis. The patient improved transiently but presented two months later with contralateral pleural effusion. Repeat thoracoscopy demonstrated multiple "sago-like" nodules, and pleural biopsy confirmed granulomatous inflammation with acid-fast bacilli (AFB).
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