Evidence map›Paper›PMID 41477401›Full record

ArticleCureus2025

Sudden Death in a Child Revealing a Multifocal Cardiac Fibroma: A Hidden Lethal Threat.

Achref Miry, Mohammed Tbouda, Kenza Oqbani, Soulaymane Dachi, Sanae Abbaoui

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Achref MiryPathology and Laboratory Medicine, Faculty of Medicine and Pharmacy of Agadir, Agadir, MAR.
Mohammed TboudaPathology, Oued Eddahab Military Hospital, Agadir, MAR.
Kenza OqbaniPathology, Souss Massa University Hospital, Agadir, MAR.
Soulaymane DachiPathology, Souss Massa University Hospital, Agadir, MAR.
Sanae AbbaouiPathology, Souss Massa University Hospital, Agadir, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite their benign histology, cardiac fibromas can cause life-threatening complications, including arrhythmias and sudden death. We report the case of a previously healthy four-year-old boy who collapsed suddenly after a minor fall. Despite immediate resuscitation efforts, he was declared dead. Autopsy revealed an enlarged heart with a large, firm, white intramyocardial mass measuring 5.5 × 4.5 × 3.0 cm in the lateral wall of the left ventricle, compressing the ventricular cavity. Three additional epicardial nodules were also identified. Histologic examination showed spindle cell proliferation with dense collagenous stroma, low mitotic activity, and no atypia or necrosis, consistent with multifocal cardiac fibroma. This case illustrates the silent yet potentially lethal nature of cardiac fibromas in children. Multifocal presentation is extremely rare and can remain undiagnosed until sudden death occurs. Awareness of such tumors and early cardiac imaging may help prevent fatal outcomes in pediatric populations.

Indexed as

cardiac fibromafibrous neoplasmmultifocal cardiac lesionpediatric cardiac tumorsudden death

Identifiers

PMID41477401
PMCPMC12750115

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.