Silent Storm: Advanced Heart Failure in a Young Female Patient With Systemic Lupus Erythematosus.

Chris Sani, Godslove Bonnah, Dea Thomas, Victor Freitas De Souza, Tiffany Li, Ahmad Jallad

Abstract readCase Reports

In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chris SaniInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.

Godslove BonnahInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.

Dea ThomasInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.

Victor Freitas De SouzaCardiology, State University of New York Downstate Health Sciences University, Brooklyn, USA.

Tiffany LiInternal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.

Ahmad JalladCardiology/Electrophysiology, Staten Island University Hospital, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus is an autoimmune disorder involving autoantibody production and immune complex-mediated damage of multiple organ systems, including the heart. The complex systemic manifestations of lupus and late detection of cardiovascular involvement make it difficult to isolate a singular mechanism that causes heart failure. We present a case of a young female patient presenting with systemic lupus nephritis and Stage 4 lupus nephritis found to have advanced heart failure and associated complications. This case highlights a young patient with lupus who developed heart failure likely due to myocarditis, underscoring the need for early cardiovascular monitoring and targeted research to improve outcomes in this high-risk population. Lupus leading to heart failure is likely caused by a multifaceted approach; further studies are needed to tailor treatment strategies for these patients that can reduce the risk of heart failure.

Indexed as

end-stage renal diseaseheart failure with reduced ejection fractionlupus myocarditissecondary pneumothoraxsle and lupus nephritissystemic lupus erythematosus disease

Identifiers

PMID41477395

DOI10.7759/cureus.98076

PMCPMC12750473

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.