Evidence map›Paper›PMID 41477297›Full record

ArticlePrecision radiation oncology2025

Activity-dependent transit dose assessment in

Daniel Liu, Emily Draeger, Christopher J Tien, Fada Guan

Abstract read
In one paragraph

Article in Precision radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Activity-dependent transit dose assessment inPrecision radiation oncology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel LiuDepartment of Physics Yale University New Haven USA.
Emily DraegerDepartment of Therapeutic Radiology Yale University School of Medicine New Haven USA.
Christopher J TienDepartment of Therapeutic Radiology Yale University School of Medicine New Haven USA.
Fada GuanDepartment of Radiation Physics The University of Texas MD Anderson Cancer Center Houston USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To characterize the newly released GafChromic Methods: EBT4 film was used to measure dose at 3 mm depth from a horizontally oriented Leipzig-style surface applicator connected to a Results: EBT4 film demonstrated excellent dose-response linearity with nominal dwell time (adjusted R Conclusions: This study validates EBT4 film as a reliable tool for transit dose measurement in surface brachytherapy. The observed non-linear relationship between transit dose and source activity reveals the critical influence of experimental setup variables, particularly source guide tube geometry, which affects the source-to-target distance during transit. These findings demonstrate that transit dose is impacted by multiple interdependent factors including source activity, guide tube configuration, and setup geometry. For clinical applications, this highlights the importance of standardized setup protocols and empirical measurement for accurate transit dose assessment.

Indexed as

High‐dose‐rate brachytherapyLeipzig surface applicatorradiochromic filmtransit dose

Identifiers

PMID41477297
PMCPMC12750306

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.