Evidence map›Paper›PMID 41477282›Full record

ArticleJournal of pharmacopuncture2025

Optimizing a Natural Oil-Based Sertaconazole Nitrate Organogel: enhanced antifungal activity through

Piyush Jain, Shashikant Chandrakar, Pushpa Prasad Gupta, Ravindra Kumar Pandey, Bina Gidwani

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In one paragraph

Article in Journal of pharmacopuncture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Piyush JainDepartment of Pharmacy, Columbia Institute of Pharmacy, Raipur, India.ORCID https://orcid.org/0009-0009-0976-6444
Shashikant ChandrakarDepartment of Pharmacy, Columbia Institute of Pharmacy, Raipur, India.ORCID https://orcid.org/0009-0008-4749-3072
Pushpa Prasad GuptaDepartment of Pharmacy, Chhatrapati Shivaji Institute of Pharmacy, Durg, India.ORCID https://orcid.org/0000-0002-1057-9197
Ravindra Kumar PandeyDepartment of Pharmacy, Columbia Institute of Pharmacy, Raipur, India.ORCID https://orcid.org/0000-0001-8284-6269
Bina GidwaniDepartment of Pharmacy, Columbia Institute of Pharmacy, Raipur, India.ORCID https://orcid.org/0000-0003-1257-723X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to develop and optimize a topical organogel formulation of Sertaconazole nitrate (SN) using Cinnamon oil (CO) to enhance antifungal activity and improve dermal drug delivery. Methods: A 3 Results: The organogels had a skin-friendly pH ranging from 6.11 to 6.99, VS between 0.39 and 0.49 Pa.s, and SP from 20.40 to 26.45 g.cm/s Conclusion: The optimized Sertaconazole nitrate organogel (SNO) with CO is a stable, safe, and effective topical delivery system that enhances drug penetration and antifungal efficacy, making it a promising option for dermal antifungal therapy.

Indexed as

Box-Behnken designcinnamon oilmicro-irradiation assisted techniquesorganogelresponse surface techniqueSertaconazole nitrate

Identifiers

PMID41477282
PMCPMC12745368

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.