ArticleJournal of pharmacopuncture2025
Anti-Inflammatory Effect of
Article in Journal of pharmacopuncture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Keratinocytes, the predominant cells in the uppermost layer of the skin, serve as theprimary protection against environmental threats. These cells exhibit activation in the presence of physical trauma, ultraviolet radiation, chemical agents, or allergenic substances. Once activated, keratinocytes release a variety of immunomodulatory soluble mediators that initiate and propagate the inflammatory response. However, dysregulation of this response and the consequent overactivation of pro-inflammatory mediators within the skin may contribute to the pathogenesis of diverse conditions, including cancer, psoriasis, chronic inflammation, autoimmune diseases, hyperpigmentation, and skin aging. Thus, downregulating pro-inflammatory mediators and recovering the physiological balance between factors that promote and those that counteract inflammation represent crucial steps in managing inflammatory skin disorders. Valued in folk medicine for its anti-inflammatory effects, Methods: This investigation sought to determine the anti-inflammatory properties of an ethanolic extract of Results: The extract's analysis revealed the presence of polyphenols and flavonoids, with chlorogenic acid identified as the predominant polyphenol. Notably, it effectively counteracted the LPS-induced elevation in NO production and also reduced release of pro-inflammatory cytokines such as IL-6, TNF-α, and IL-1β. Additionally, the extract exhibited the potential to accelerate wound closure in an Conclusion: The present findings suggest that
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.