ArticleJournal of geriatric cardiology : JGC2025
Impact of coronary artery involvement on mortality in patients with acute type A aortic dissection: results from a large-scale cohort study.
Article in Journal of geriatric cardiology : JGC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundUnderstanding the type and extent of coronary artery involvement in patients with acute type A aortic dissection (ATAAD) is vital for surgical planning. The Neri classification has been proposed as a guide for surgical strategies, however, its prognostic impact on postoperative mortality rates remains understudied in large-scale cohorts.
methodsWe reviewed 600 ATAAD patients who underwent surgery and coronary computed tomography angiography from 2016 to 2020 at Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Patients were classified based on the Neri classification system: no coronary artery involvement, type A (ostial involvement), type B (dissection in coronary body), and type C (circumferential detachment or complete avulsion). The primary endpoint was 30-day mortality.
resultsOverall, 28.3% of the patients had coronary artery involvement, with Neri type A, Neri type B, and Neri type C accounting for 13.3%, 11.2%, and 3.8%, respectively. The right coronary artery was more frequently involved (25.3%) than the left coronary artery (8.0%). In the unadjusted analysis, patients with coronary artery involvement exhibited a numerically higher 30-day mortality compared to those without (5.3%
conclusionsIn patients with ATAAD who undergo surgery, the presence of coronary artery involvement is significantly associated with an increased risk of 30-day mortality. Proactive coronary artery bypass grafting may potentially mitigate the adverse impact of coronary artery involvement on 30-day mortality.
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