ArticleJournal of geriatric cardiology : JGC2025
A clinical nomogram for predicting major adverse cardiovascular and cerebrovascular events in elderly Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention: development and validation in a real-world cohort.
Article in Journal of geriatric cardiology : JGC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAs the global population ages, the number of elderly patients with acute coronary syndrome (ACS) rises. However, prognostic assessment tools for elderly patients with ACS remain lacking, particularly in the Chinese population. This study aimed to develop and validate a nomogram to predict 2-year major adverse cardiovascular and cerebrovascular events (MACCE) in elderly Chinese patients with ACS.
methodsA retrospective analysis was conducted using two independent cohorts of ACS patients aged ≥ 65 years who underwent percutaneous coronary intervention: the derivation cohort (
resultsThe 2-year incidence of MACCE was 12.5% (
conclusionsThis newly developed nomogram provides a reliable tool for individualized prediction of the 2-year MACCE risk in elderly Chinese patients with ACS who underwent percutaneous coronary intervention. It outperformed the GRACE score in both discrimmination and calibration and may help improve clinical decision-making and personalized risk stratification in this vulnerable population.
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