Evidence map›Paper›PMID 41477090›Full record

ReviewArchives of rehabilitation research and clinical translation2025

Cognitive Impairment Highly Prevalent and Associated With Reduced Physical Function in Older Veteran Clinical Exercise Program.

Stacy Schantz Wilkins, Jin J Zhou, Rebecca J Melrose, Mia Delgadillo, Elisa F Ogawa, Steven C Castle, Megan Pearson, Rebekah Harris, Jonathan Wanagat, Jamie Giffuni and 8 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Archives of rehabilitation research and clinical translation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Stacy Schantz WilkinsGreater Los Angeles VA Medical Center, Mental Health Department, Los Angeles, CA.
Jin J ZhouUniversity of California School of Public Health, Dept of Biostatistics, Los Angeles, CA.
Rebecca J MelroseGreater Los Angeles VA Medical Center, Mental Health Department, Los Angeles, CA.
Mia DelgadilloGreater Los Angeles VA Medical Center, Mental Health Department, Los Angeles, CA.
Elisa F OgawaVA Boston Healthcare System, Geriatric Research Education and Clinical Center, Boston, MA.
Steven C CastleUniversity of California Los Angeles David Geffen School of Medicine, Los Angeles, CA.
Megan PearsonVA Medical Center, Geriatric Research, Education, and Clinical Center, Durham, NC.
Rebekah HarrisVA Boston Healthcare System, Geriatric Research Education and Clinical Center, Boston, MA.
Jonathan WanagatUniversity of California Los Angeles David Geffen School of Medicine, Los Angeles, CA.
Jamie GiffuniBaltimore VA Medical Center, Geriatric Research Education and Clinical Center, Baltimore, MD.
Neil AlexanderVA Ann Arbor Geriatric Research Education and Clinical Center, Ann Arbor, MI.
Adam D GepnerWilliam S. Middleton Memorial Veterans Hospital, Division of Cardiovascular Medicine, Madison, WI.
Lauren M AbbateVA Eastern Colorado Health Care System, Geriatric Research, Education and Clinical Center, Aurora, CO.
Daniel E FormanPittsburgh GRECC, VA Pittsburgh Healthcare System, Pittsburgh, PA.
Odessa AddisonBaltimore VA Medical Center, Geriatric Research Education and Clinical Center, Baltimore, MD.
Monica C SerraBaltimore VA Medical Center, Geriatric Research Education and Clinical Center, Baltimore, MD.
Katherine S HallVA Medical Center, Geriatric Research, Education, and Clinical Center, Durham, NC.
Cathy C LeeUniversity of California Los Angeles David Geffen School of Medicine, Los Angeles, CA.

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI CATHLEEN S COLON-EMERIC, Susan Nicole Hastings · 2006 to 2026
$24.6M
NIA NIH HHS P30 AG028716RRD VA I01 RX003120RRD VA IK2 RX005294
6 · The paper itself

Abstract

Objective: To evaluate cognition at entry into the Gerofit program and its association with physical function. Design: Retrospective observational cross-sectional design. Setting: Gerofit outpatient clinical exercise programs at multiple Veterans Affairs Medical Centers from 2021 to 2023. Participants: New enrollees (N=1172) completed measures of lower and upper extremity strength, balance, cardiovascular endurance, and measures of global cognition (telephone Montreal Cognitive Assessment, tMoCA) and cognitive set shifting (Oral Trail Making Test B). Dementia diagnosis in the medical record was exclusionary. Interventions: Not applicable. Main Outcome Measures: Relationship between physical and cognitive function, self-rated memory change, and demographics were evaluated by linear regression. Results: Mean age was 75 years. 78% of participants were White and 20% Black; 88% were men. Mean tMoCA score was 17.39. tMoCA and Oral Trail Making Test B scores were significantly associated with lower extremity strength ( Conclusions: Global cognitive functioning was below the cutoff for normal cognition in 61% of participants, suggesting mild cognitive impairment is common in older exercise program enrollees. Lower cognitive scores were related to both reduced strength and endurance.

Indexed as

Age-friendlyCognitionGerofitMoCAOlder adultPhysical activityRehabilitation

Identifiers

PMID41477090
PMCPMC12750347

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.